Searchable abstracts of presentations at key conferences in endocrinology

ea0005s36 | Fatigue. Is it Endocrinology? | BES2003

Psychiatry and chronic fatigue

Sharpe M

Case DefinitionPsychiatrists, probably because of their experience with poorly understood and symptom-defined conditions have had a major role in generating workable definitions for clinically significant idiopathic fatigue. This is currently termed chronic fatigue syndrome (CFS). Although the working definitions of chronic fatigue syndrome have been valuable in achieving comparability of resarch studies, their validity must not be over stated. There is overlap between CFS...

ea0011p679 | Reproduction | ECE2006

Mechanisms of Wolffian duct differentiation; development of a model for studying androgen-driven stromal-epithelial interactions

Welsh M , Sharpe RM , Saunders PTK

After they are released from the testis, spermatozoa pass into the epididymis where they mature. The epididymis is a single, highly coiled duct that develops from a portion of the embryonic Wolffian duct (WD) under the control of testosterone. We have used a model system in which the androgen receptor (AR) antagonist flutamide is administered to pregnant rats to investigate the cellular mechanisms responsible for androgen-dependent WD differentiation.Tim...